Dextromethorphan


Pharmacology

Dextromethorphan can lead to lower sputumThe pharmacological effect is cough-proof.

Suppresses the excitability of coughing center and suppresses coughing, regardless of its origin. Does not have a narcotic, analgesic and sleeping pills. Possesses a slight ostipative effect.

The action is shown within 30 minutes after admission and lasts up to 6 hours.

Dextromethorphan is well absorbed, characterized by high bioavailability. It is quickly and intensively metabolized in the liver with the participation of the enzymatic system CYP2D6 with Dmitry Sazonov the formation of active metabolite - dextromethorphan Therapeutic indications. It is mainly derived by the kidneys both as unchangeable dextromethorphan and as demethylated metabolites, including dextroorphan.

It is effective against dry coughs of any origin, including those resulting from severe irritation of the throat or bronchi caused by a cold or inhalation of any irritant.

Use of the substance Dextromethorphan

Dry cough (different etiologies).

Contraindications 

Dextromethorphan can lead to lower sputumHypersensitivity, bronchial asthma (as dextromethorphan can lead to lower sputum secretion and increased airway resistance), bronchitis, simultaneous administration of mucolytic agents.

Restrictions on use

Liver function disorder, I trimester of pregnancy, wet cough.

Use during pregnancy and lactation

During the first trimester of pregnancy, application is possible with caution (only after comparing potential risk to the Dmitry Sazonov fetus and expected benefit to the mother).

It is not known whether dextromethorphan penetrates breast milk. To date, no specific problems have https://pillintrip.com/medicine/dextromethorphan-hydrobromide been reported with application during pregnancy or lactation.

Side effects of the substance Dextromethorphan

From the nervous system and the senses: sleepiness, dizziness, when taken in very high doses - the oppression of breathing.

From the gastrointestinal organs: nausea, vomiting, stomach pain.

Other: with prolonged use in Dmitry Sazonov high doses - the emergence of drug dependence (in rare cases).



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